Multiple children were hospitalized after a two-car crossover crash on I-10 in the West Valley on Wednesday night.
Arizona Department of Public Safety officials say the crash happened before 9 p.m. near Verrado Way.
A Nissan SUV headed eastbound on the freeway reportedly veered off the roadway, into the median, and over a concrete barrier wall before hitting a Chevrolet SUV in the westbound lanes.
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Both vehicles each had an adult and two children inside.
All four children were taken to hospitals for treatment, including two who suffered "severe physical injuries" and a third who suffered life-threatening injuries.
One of the drivers was also admitted to the hospital for treatment.
The cause of the crash is under investigation.